Prof Mark McGuire






Areas of Interests

  • arrhythmias (abnormal heart rhythms)
  • atrial fibrillation
  • catheter ablation
  • pacemakers
  • implantable defibrillators


Suite 204, RPAH Medical Centre 100 Carillon Ave Newtown NSW 2042


02 9519 5922


02 9519 5944



VMO Mater Hospital, Senior Staff Specialist RPAH & POW, Professor University of Sydney


Professor Mark McGuire is a cardiologist and specialist cardiac electrophysiologist (a doctor who specialises in the treatment of abnormal heart rhythms).

He graduated in Medicine from the University of New South Wales with First Class Honours. He trained in internal medicine and cardiology at St Vincent’s and Westmead Hospitals in Sydney. He was Clinical Superintendent of Westmead Hospital in 1991 and 1992. He holds a Doctor of Philosophy Degree in Medicine from the University of Sydney and spent 2 years doing post-doctoral research in Amsterdam at the Academic Medical Centre and University of Amsterdam. Professor McGuire was awarded the prestigious Neil Hamilton Fairley Scholarship by The National Health and Medical Research Council. He returned to Royal Prince Alfred Hospital in 1994, where he founded the Cardiac Arrhythmia Service. He is a Senior Staff Specialist at Royal Prince Alfred and Prince of Wales Hospitals and is a Visiting Medical Officer at the Mater Hospital, the Prince of Wales Private Hospital, Eastern Heart Clinic and Macquarie University Hospital. He is a Clinical Professor of Medicine in the University of Sydney and has delivered numerous papers to national and international scientific meetings. He is chairman of Cardiovascular Medicine at the Mater Hospital.

Professor McGuire is a Fellow of the Royal Australasian College of Physicians and the Cardiac Society of Australia and New Zealand.

Professor McGuire regularly performs cardiac electrophysiological studies and catheter ablations for abnormal heart rhythms and has performed more than 8,000 of these procedures, including more than 500 ablation procedures for atrial fibrillation. Professor McGuire’s research interests include supraventricular tachycardia, sudden death in the young, arrhythmias in patients with complex congenital heart disease, atrial fibrillation and, in particular, the biophysics of cryoablation of atrial fibrillation. He teaches medical students at the University of Sydney. He has served on the editorial boards of two major medical journals specialising in abnormal heart rhythms (Heart Rhythm and the Journal of Cardiovascular Electrophysiology).